Diabetes & metabolic generics
DPP-4 inhibitors, SGLT2 inhibitors, GLP-1 agonists and insulin analogues — the highest-volume chronic therapy in the region.
11 molecules. Open any card for the full monograph and manufacturer list.
Sitagliptin High demand
Originator: Januvia · Merck Sharp & Dohme (MSD), a subsidiary of Merck & Co., Inc.
US (FDA): adjunct to diet and exercise to improve glycemic control in adults with type 2 diabete
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Vildagliptin
Originator: Galvus · Novartis
EU (EMA / UK SmPC): treatment of type 2 diabetes mellitus in adults as monotherapy in patients i
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Linagliptin
Originator: Tradjenta · Boehringer Ingelheim (marketed in the US by Boehringer Ingelheim Pharmaceuticals, Inc.; co-promoted with Eli Lilly in several markets)
US (FDA): adjunct to diet and exercise to improve glycemic control in adults with type 2 diabete
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Dapagliflozin High demand
Originator: Forxiga · AstraZeneca (originally developed with Bristol-Myers Squibb)
As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes me
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Empagliflozin High demand
Originator: Jardiance · Boehringer Ingelheim, co-marketed with Eli Lilly and Company (licensed from Boehringer Ingelheim International GmbH)
To reduce the risk of cardiovascular death and hospitalization for heart failure in adults with
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Canagliflozin
Originator: Invokana · Janssen Pharmaceuticals (Johnson & Johnson), licensed from Mitsubishi Tanabe Pharma
As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes me
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Pioglitazone
Originator: Actos; Actoplus Met and Actoplus Met XR · Takeda Pharmaceutical Company (first US approval 1999)
As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes me
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Liraglutide
Originator: Victoza · Novo Nordisk
As an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients
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Insulin Glargine High demand
Originator: Lantus · Sanofi
To improve glycemic control in adult and pediatric patients with diabetes mellitus (Lantus, US l
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Insulin Degludec
Originator: Tresiba · Novo Nordisk
To improve glycemic control in adults with diabetes mellitus (US label of 2015)
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Insulin Aspart
Originator: NovoRapid · Novo Nordisk
To improve glycemic control in adults and children with diabetes mellitus (NovoLog, US label)
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Therapeutic areas
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